Toxins
Toxins
Enzo Life Sciences Cylindrospermopsin (1mg). CAS: 143545-90-8
Tricyclic alkaloid hepatotoxin. Exhibits a completely different mechanism of toxicity than microcystins. Protein synthesis inhibitor. Might be carcinogenic. Inhibits pyrimidine nucleotide synthesis. Purity: ≥95% (HPLC). Appearance: Glassy solid. Solubility: Soluble in water, methanol or DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Hydroxytyrosol. acetate (50mg). CAS: 69039-02-7
Antioxidant comparable to resveratrol (BML-FR104). Is converted to hydroxytyrosol through hydrolysis by esterases. Reaches full oxygen radical absorbance capacity (ORAC) when converted to free hydoxytyrosol. ORAC values of hydroxytyrosol are about 50% higher than resveratrol, 10-fold higher than L(+)-ascorbic acid and 4-fold higher than (-)-epicatechin. Has been shown to have anticancer and antiviral effects. Antibacterial at 400µg/mL against Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. Alternative name: HTS, 2-(3,4-Dihydroxyphenyl)-ethanol. Purity: ≥98% (HPLC). Appearance: White to off-white powder. Solubility: Freely soluble in organic solvents; slightly soluble in water (10mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences C. difficile toxin A (50µg)
Potent enterotoxin. Potent enterotoxin. Alternative name: Clostridium difficile toxin A. Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains 0.05M HEPES, 0.15M sodium chloride and 5% sucrose. Source: From Clostridium difficile, strain VPI10463. Long Term Storage: +4°C. Applications: ELISA LINE assay, Cytotoxicity studies, Antibody capture.
Enzo Life Sciences Tetanus toxoid (100 µg)
Inactivation with formaldehyde leads to non-toxic form of tetanus toxin. Produced from tetanus toxin by inactivation with formaldehyde. The resulting toxoid is essentially non-toxic. Synonyms: Formaldehyde inactivated tetanus toxin. MW: ~150kDa. UniProt ID: P04958. Formulation: Lyophilized.
Enzo Life Sciences Bordetella pertussis toxin (50µg). CAS: 70323-44-3
Native protein. Native protein. Alternative name: Islet-activating protein, PTX. Purity: ≥98%. Formulation: Lyophilized. Contains 0.05M sodium phosphate and 0.5M sodium chloride. Source: From Bordetella pertussis, strain NCTC 10739. Long Term Storage: +4°C. Applications: ELISA LINE assay, Cytotoxicity studies, Antibody capture.
Enzo Life Sciences C. difficile toxin B (50µg)
Extremely potent cytotoxin. Extremely potent cytotoxin. Alternative name: Clostridium difficile toxin B. Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains 0.05M HEPES, 0.15M sodium chloride and 5% sucrose. Source: From Clostridium difficile, strain VPI10463. Long Term Storage: +4°C. Applications: ELISA LINE assay, Cytotoxicity studies, Antibody capture.
Enzo Life Sciences Ansamitocin P-3 (1 mg). CAS: 66547-09-9
Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. It shares the same binding site as rhizoxin and phomopsin A on porcine brain tubulin. Maytansine and its analogs cause extensive disassembly of the microtubule and totally prevent tubulin spiralization. Purity: ≥93% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Cytochalasin B, (5mg), CAS Number: 14930-96-2
Ultra-pure; inhibits actin polymerization. Cytochalasin B is a cell-permeable fungal toxin which binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. It also inhibits monosaccharide transport across cell membranes. inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells. Formula: C29H37NO5. MW: 479.6. CAS Number: 14930-96-2. Purity: ≥98% (HPLC, TLC). Appearance: White to off-white solid. Solubility: Soluble in methanol or DMSO (20mg/ml). Long Term Storage: -20°C
Enzo Life Sciences T-2 Toxin (1mg). CAS: 21259-20-1
Mycotoxin. Induces DNA damage and apoptosis. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in the brain. Alternative name: 4beta,15-Diacetoxy-3alpha-hydroxy-8alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene. Purity: ≥98% (TLC). Appearance: White to off-white crystalline solid. Solubility: Soluble in methylene chloride (5mg/ml) or chloroform. Long Term Storage: -20°C.
Enzo Life Sciences T-2 Toxin (5mg). CAS: 21259-20-1
Mycotoxin. Induces DNA damage and apoptosis. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in the brain. Alternative name: 4beta,15-Diacetoxy-3alpha-hydroxy-8alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene. Purity: ≥98% (TLC). Solubility: Soluble in methylene chloride (5mg/ml) or chloroform. Long Term Storage: -20°C.
Enzo Life Sciences Calyculin A, (100µg), CAS Number: 101932-71-2
Inhibitor of PP1 and PP2A. Formula: C50H81N4O15P. MW: 1009.2. CAS Number: 101932-71-2. Purity: ≥98% (HPLC). Appearance: Clear film or white crystalline powder. Solubility: Soluble in DMSO, 100% ethanol and dimethyl formamide. Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. Long Term Storage: -20°C
Enzo Life Sciences omega-Agatoxin IVA (100µg). CAS: 145017-83-0
Selective P-type Ca2+ channel blocker. Fast acting and potent neurotoxin. Purity: ≥98%. Appearance: Lyophilized. Solubility: Soluble in water. Long Term Storage: -20°C.
Enzo Life Sciences alpha-Latrotoxin (40µg). CAS: 65988-34-3
Causes massive neurotransmitter release from a wide variety of central and peripheral synaptic junctions of vertebrates using Ca2+-dependent and Ca2+-independent pathways. A useful pharmacological tool in the studies of synaptic vesicles exocytosis of different neutrotransmitters. Causes massive neurotransmitter release from a wide variety of central and peripheral synaptic junctions of vertebrates using Ca2+-dependent and Ca2+-independent pathways. A useful pharmacological tool in the studies of synaptic vesicles exocytosis of different neutrotransmitters. Purity: ≥97%. Formulation: Lyophilized. Source: Isolated from Latrodectus tredecimguttatus. Long Term Storage: -20°C.
Enzo Life Sciences Penitrem A (5mg). CAS: 12627-35-9
Fungal mycotoxin. Selective, irreversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (100% block at 10 nM). Increases spontaneous release of GABA and aspartate from cerebrocortical synaptosomes in rat neuromuscular junction. Alternative name: NSC 354845, Tremortin A. Purity: ≥95% (HPLC, TLC). Solubility: Soluble in organic solvents such as methanol, acetone or DMSO. Long Term Storage: -20°C.
Enzo Life Sciences 2-Methoxyestradiol (50 mg). CAS: 362-07-2
An endogenous estrogen metabolite with low affinity for the estrogen receptor but which disrupts microtubule function. Potent inhibitor of endothelial cell proliferation and migration. Inhibits bFGF and VEGF-induced corneal neovascularization in mice. Posttranscriptionally downregulates HIF-1α expression. Alternative name: 2-ME. Purity: ≥95% (TLC). Long Term Storage: Ambient.