Organic compounds
Organic compounds
Organic compounds are a class of chemical compounds that contain one or more atoms of carbon covalently bonded to each other and atoms of other elements such as hydrogen, oxygen, nitrogen, sulfur, etc.
Compounds or allotropes of carbon that contain only carbon atoms are classified as inorganic compounds and exhibit novel properties.
This class of chemicals has a wide range of applications and includes graphite, diamond, and the more recently discovered graphene, fullerenes, and other carbon nanotubes. In fact, the majority of elements in the periodic table of elements are inorganic compounds.
Enzo Life Sciences GSNO (25mg). CAS: 57564-91-7
NO donor which spontaneously releases NO under physiological conditions. Half-life of 159 hours under physiological conditions. Selectively inhibits platelet activation and displays cardioprotective effects. Inhibits NF-κB activation. Inhibits endothelial cell proliferation and induces apoptosis in T cells. Alternative name: S-Nitroso-L-glutathione, N-(N-L-gamma-Glutamyl-S-nitroso-L-cysteinyl)-glycine. Purity: ≥98% (HPLC). Solubility: Soluble in water (25mg/ml), DMSO (20mg/ml) or PBS; sparingly soluble in 100% ethanol, methanol or dimethyl formamide. Long Term Storage: -20°C.
Enzo Life Sciences Gefitinib-based PROTAC 3 (10mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.
Enzo Life Sciences Gefitinib-based PROTAC 3 (50mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.
Enzo Life Sciences Gefitinib-based PROTAC 3 (25mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.
Enzo Life Sciences A1874 (10mg). CAS: 2064292-12-0
A1874 is a nutlin-based PROTAC targeting on BRD4, consist of a BRD4-ligand JQ1 linked to a MDM2 E3 ligase ligand RG7388. A1874 possesses dual function as it dose-dependently degraded its target BRD4, accompanied with the downregulation of c-MYC, as well as stabilization of P53 and upregulated P21 due to the efficient engagement of MDM2 by RG7388. Purity: ≥98%. Long Term Storage: -20°C.
Enzo Life Sciences C8 Ceramide (25 mg). CAS: 74713-59-0
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It induces phosphorylation of epidermal growth factor receptor on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase and induces apoptosis. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences U-73122 (25 mg). CAS: 112648-68-7
Inhibits agonist induced phospholipase C (PLC) activation (IC50=1-2.1 µM) in human platelets. It also inhibits agonist induced down-regulation of muscarinic receptors in SK-N-SH neuroblastoma cells. It is a useful tool to investigate receptor-mediated PI turnover in signal transduction. It is a potent inhibitor of human neutrophil adhesion to biological surfaces as well as adhesion-dependent granule exocytosis and oxidative burst. Inhibits 5-lipoxygenase in vivo and in vitro (IC50 = 30nM for recombinant enzyme and 2.4µM for PMNL homogenates). Alternative name: 1-(6-((17beta-3-methoxyestra-1 3 5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2 5-dione. Purity: ≥98% (HPLC). Solubility: Soluble in methylene chloride or chloroform. Slightly soluble in DMSO (2mg/ml) or 100% ethanol (1mg/ml), sparingly soluble in aqueous solutions. . Long Term Storage: Ambient.
Enzo Life Sciences TN-16 (50 mg). CAS: 33016-12-5
A novel synthetic inhibitor of microtubule formation which binds to the colchicine site. It prevents the stabilization of microtubules in taxol-treated cells. Blocks the cell cycle in M-phase. Purity: ≥97% (HPLC). Long Term Storage: Ambient.
Enzo Life Sciences FURA-2 AM (ultra pure) (1mg). CAS: 108964-32-5
Fura-2 acetomethoxy (AM) is one of the most widely used calcium indicators for homogenous quantitative dual wavelength ratiometric cell measurements. Fura-2 AM is particularly useful for digital imaging microscopy. It is less susceptible to photobleaching than Indo-1. The probe is excited only by UV light, which results in significantly less interference by visible wavelength excitable fluorescent compounds. One application of the probe is as a useful counter screen tool for GPCR and calcium channel hits identified using calcium indicators excited at 488nm in primary screens. Fura-2 AM can be easily loaded into cells by passive incubation. Wavelength Maxima: Excitation 370nm, Emission 476nm Alternative name: 1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2'-amino-5'-methyl-phenoxy)ethane-N,N,N',N'-tetraacetic acid, pentaacetoxymethyl ester. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Hapten 4-hydroxy-3-nitrophenyl acetyl NP Recombinant monoclonal antibody (B1-8) (Mouse IgG1 lambda) (200µg)
Clone: B1-8. Isotype: IgG1λ. Immunogen: Hapten-protein conjugated NP12-chicken gammaglobulin (CG). Applications: Flow Cytometry, WB. Purity: Protein A affinity purified. Formulation: Liquid. In PBS containing 0.02% Proclin 300.
Enzo Life Sciences Alectinib. hydrochloride (50mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Alectinib. hydrochloride (200mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Ceritinib (free base) (100mg). CAS: 1032900-25-6
Ceritinib is a selective inhibitor of ALK, a target found in metastatic non-small cell lung cancer. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Dabrafenib (free base) (200mg). CAS: 1195765-45-7
Dabrafenib is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Dacomitinib (free base) (25mg). CAS: 1110813-31-4
Dacomitinib is a potent, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.