Search results for "Fluidigm"
Fluidigm Corp ANTI-HU CD123 -151EU
CD123 is the transmembrane α chain of the interleukin-3 (IL-3) receptor. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Fluidigm Corp ANTI-HU CD38 -172YB
CD38, also known as T10, is a transmembrane glycoprotein. It is expressed at variable levels across most human hematopoietic cells and in other tissues (i.e., brain, muscle, kidney). It is expressed at the highest levels on plasma cells (memory B cells) as well as activated T and B cells.
Fluidigm Corp ANTI-MOUSE CD3E -152SM
Mouse CD3ε is a 20 kDa subunit of the TCR complex. There are three CD3 subunits, epsilon, gamma, and delta, and they are all required for proper assembly, trafficking, and surface expression of the TCR complex. CD3 is expressed at different levels on thymocytes during T cell differentiation and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis, depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.
Fluidigm Corp ANTI-HUIL-17A -164DY
Interleukin-17A (IL-17A) is a cytokine in a family that includes 6 structurally related proteins (IL-17A through IL-17F), though most activities seem to be mediated primarily by IL-17A. IL-17 induces neutrophil-rich inflammatory reactions, such as stimulating the production of chemokines and other cytokines, and stimulates the production of antimicrobial substances. It is primarily produced by a subset of T cells when activated (Th17 cells).
Fluidigm Corp ANTI-MO/HU CD44 -171YB
CD44, also known as Hermes, Pgp-1, H-CAM, and HUTCH, is a cell surface glycoprotein. It is involved in a variety of cellular functions including: cell-to-cell interactions, adhesion, homing, and migration and is a receptor for haluronic acid. CD44 is expressed on a number of cell types including leukocytes, endothilial cells, hepatocytes, and mesenchymal cells and has been reported to be a marker for memory cell subsets.
Fluidigm Corp ANTI-HU CD127 -176YB
CD127, also known as the IL-7 receptor α chain or IL-7α, is a 60–90 kDa type I transmembrane glycoprotein. It is a heterodimer consisting of IL-7Rα (CD127) and a common-γ chain receptor (CD132), which is shared with various cytokines including IL-2,-4,-9,-13,-15 and -21. CD127 is expressed on immature B through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. It can be a useful marker for identifying memory and effector T cells and differentiation of Treg and conventional T cells.
Fluidigm Corp Anti-Mouse CD39 (24DMS1)-142Nd 25 Tests
CD39 is expressed in B cells, subsets of dendritic cells, most monocytes, and CD4+CD25+ immunosuppressive regulatory T (Treg) cells.
Fluidigm Corp Anti-Cross GFAP (GA5)-143Nd 100 Tests
Glial fibrillary acidic protein (GFAP) is a 49 kDa cytoskeletal type III intermediate filament and maintains cell stability, shape, motility and proliferation.
Fluidigm Corp Anti-Mouse Ly-6C (HK1.4)-150Nd 25 Tests
Ly-6C is a 14–17 kDa GPI-linked cell surface glycoprotein that is widely used to identify functionally discrete murine-circulating monocyte populations.
Fluidigm Corp Anti-Human CD23 (EBVCS-5)-164Dy 100 Tests
CD23, the low-affinity receptor for immunoglobulin E, is expressed on monocytes, mantle zone B cells, mature B cells, and follicular dendritic cells and at low levels on T, NK, and Langerhans cells and platelets.
Fluidigm Corp Anti-Mouse CD169/Siglec-1 (3D6.112)-170Er 25 Tests
Anti-Mouse CD169/Siglec-1 (3D6.112)-170Er 25 Tests
Fluidigm Corp Anti-Human IgM (MHM-88)-172Yb 100 Tests
IgM is the first immunoglobulin made by B cells in the immune response. Surface IgM is expressed on immature and mature B cells, while IgM heavy (?) chain is expressed intracellularly in pre-B cells.
Fluidigm Corp Anti-Human CD16 (3G8)-209Bi 25 Tests
CD16, also known as low-affinity IgG receptor III (Fc?RIII), is a polypeptide-anchored transmembrane protein.