Lipids and Lipid Derivatives
Lipids and Lipid Derivatives
Enzo Life Sciences Noladin ether (5mg). CAS: 222723-55-9
Endogenous cannabinoid agonist isolated from porcine brain. Binds specifically to CB1 (Ki=21.2nM) and CB2 (Ki=>3µM) receptors. Causes sedation hypothermia, intestinal immobility and mild antinociception in mice. Chemically stable, but less potent than 2-arachidonoylglycerol (BML-FA028) with an endogenous half-life time of hours rather than minutes. Alternative name: 2-Arachidonyl glyceryl ether, 2-AG ether, 5Z,8Z,11Z,14Z-Eicosatetraen-2-glyceryl ether. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (40mg/ml) or ethanol (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences 5,8,11,14-Eicosatetraynoic acid (100mg). CAS: 1191-85-1
Inhibits arachidonic acid uptake. Inhibits cyclooxygenase (ID50=8 µM) and all lipoxygenases (ID50=10, 0.3, and 0.2 µM for 5-, 12- and 15-LO respectively) in whole cells. Inhibits PLA2 and cytochrome P-450. Modulates Ca2+ entry into cells. Stimulates luteinizing hormone release from cultured pituitary cells. PPAR agonist. Alternative name: ETYA. Purity: ≥98% (TLC). Solubility: Soluble in 100% ethanol, methanol, DMSO, acetone or acetonitrile. Long Term Storage: +4°C.
Enzo Life Sciences Dihydrosphingosine, D-erythro (50 mg). CAS: 764-22-7
Biosynthetic precursor of sphingosine. Inhibitor of protein kinase C (PKC). Blocks phospholipases A2 (PLA2) and the D-sphingosine precursor. Alternative name: D-erythro-Sphingosine, Dihydro-, Sphinganine. Purity: ≥98% (TLC). Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml, warm). Long Term Storage: -20°C.
Enzo Life Sciences 3-O-Methyl-Sphingomyelin (5 mg)
3-O-Methyl-Sphingomyelin is a novel selective inhibitor of neutral sphingomyelinase, (Ki=37 µM). It is cell-permeable and does not inhibit acid sphingomyelinase. Purity: ≥98% (TLC). Solubility: Soluble in ethanol (>25 mg/ml) or DMSO (20 mg/ml@50°C). Long Term Storage: -20°C.
Enzo Life Sciences U-73343 (5 mg). CAS: 142878-12-4
Inactive analog of U-73122 (BML-ST391) which only slightly inhibits phospholipase C. May be used as a negative control. Alternative name: 1-[6-[[(17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-pyrrolidine-2,5-dione. Purity: ≥98% (HPLC). Solubility: Soluble in methylene chloride or chloroform; slightly soluble in DMSO (2mg/ml) or 100% ethanol (1mg/ml); sparingly soluble in aqueous solutions. Long Term Storage: Ambient.
Enzo Life Sciences Monophosphoryl Lipid A, (100µg), CAS Number: 1246298-63-4
TLR4 activator. Alternative Name: MPLA, Glucopyranosyl lipid adjuvant, GLA. Formula: C96H184N3O22P. MW: 1763.47. CAS Number: 1246298-63-4. Long Term Storage: +4°C
Enzo Life Sciences Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid (1g). CAS: 6217-54-5
Polyunsaturated fatty acid. Purity: ≥98%. Solubility: Soluble in ethanol, hexane and methylene chloride. Long Term Storage: -20°C.
Enzo Life Sciences Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid (100mg). CAS: 6217-54-5
Polyunsaturated fatty acid. Purity: ≥98%. Solubility: Soluble in ethanol, hexane and methylene chloride. Long Term Storage: -20°C.
Enzo Life Sciences 3-O-Methyl-Sphingomyelin (1 mg)
3-O-Methyl-Sphingomyelin is a novel selective inhibitor of neutral sphingomyelinase, (Ki=37 µM). It is cell-permeable and does not inhibit acid sphingomyelinase. Purity: ≥98% (TLC). Solubility: Soluble in ethanol (>25 mg/ml) or DMSO (20 mg/ml@50°C). Long Term Storage: -20°C.
Enzo Life Sciences Docetaxel (5 mg). CAS: 114977-28-5
Docetaxel is taxane-type antineoplastic agent structurally similar to taxol. It reversibly binds to polymerized tubulin inhibiting depolymerization. It induces apoptosis in a large number of tumor cells and is a clinically important anticancer agent. Alternative name: Taxotere. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Betulinic acid (~95%) (500mg). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Enzo Life Sciences 20-Hydroxyecdysone (10mg). CAS: 5289-74-7
Most widely occurring ecdysteroid in both plant and animal species. Controls cell death during metamorphosis of Drosophila melanogaster. Alternative name: beta-Ecdysone, 2beta,3beta,14alpha,20R,22R,25-Hexahydroxy-5beta-cholest-7-en-6-one, Ecdysterone. Purity: ≥95% HPLC. Solubility: Soluble in water, 100% ethanol, methanol, DMSO and acetic acid. Long Term Storage: -20°C.
Enzo Life Sciences AG-879 (5mg). CAS: 148741-30-4
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences 25(OH) Vitamin D Controls (1Set)
25(OH) Vitamin D Controls for use with 25(OH) Vitamin D ELISA Kit. Content: 1 high and 1 low control. Long Term Storage: -80°C. Applications: ELISA .
Enzo Life Sciences 1,2-Dilauroyl-sn-glycero-3-phosphocholine (250mg). CAS: 18194-25-7
Alternative name: DLPC. Purity: ≥99% (TLC). Appearance: White to off-white solid. Solubility: 20mg/ml soluble in chloroform:methanol:acetic acid:water (100:30:10:2.5); slightly soluble in methanol. Long Term Storage: -20°C.
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