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Bioactive Small Molecules

Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1 – 15 of 91 results
1

Tocris™ CNV Dopamine

Caged dopamine; photolysed by UV light

2

A 412997 dihydrochloride

Selective D4 agonist

CAS 1347744-96-0
Chemical Name or Material N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide
Recommended Storage Desiccate at Room Temperature
Molecular Formula C19H23N3O.2HCl
Formula Weight Observed MW: 382.33
Assay Percent Range >98%
3

Tocris Bioscience™ Eticlopride hydrochloride

D2 and D3 antagonist (D3 > D2)

CAS 97612-24-3
Solubility Soluble to 100mM in water
Chemical Name or Material 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride
Recommended Storage Desiccate at Room Temperature
Molecular Formula C17H25ClN2O3.HCl
Formula Weight Observed MW: 377.31
Assay Percent Range >99%
4

Tocris Bioscience™ Aripiprazole

High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

5

MLS 1547

G protein-biased D2 partial agonist

CAS 315698-36-3
Chemical Name or Material 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol
Recommended Storage Store at 4°C
Molecular Formula C19H19ClN4O
Formula Weight Observed MW: 354.83
Assay Percent Range >98%
6

Cayman Chemical DOPAMINE HYDROCHLORIDE 10G
SDP

Dopamine (hydrochloride)/ 10g / 62-31-7

ENCOMPASS_PREFERRED
7

Tocris Bioscience™ EPPTB

Trace amine 1 (TA1) receptor antagonist/inverse agonist

Target Trace Amine 1 (TA1) Receptor Antagonists
CAS 1110781-88-8
Purity >99%
Chemical Name or Material N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide
Recommended Storage Store at 4°C
Molecular Formula C20H21F3N2O2
Formula Weight 378.39
8

Tocris Bioscience™ Nepicastat hydrochloride

Potent and selective dopamine β-hydroxylase (DBH) inhibitor; orally bioavailable

Target Hydroxylase Inhibitors
CAS 170151-24-3
Purity >98%
Chemical Name or Material 5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride
Recommended Storage Store at -20°C
Molecular Formula C14H15F2N3S.HCl
Formula Weight 331.81
9

Tocris Bioscience™ GBR 12909 dihydrochloride

Selective DA uptake inhibitor; also σ ligand

CAS 67469-78-7
Solubility Soluble to 50mM in DMSO
Chemical Name or Material 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Recommended Storage Desiccate at Room Temperature
Molecular Formula C28H32F2N2O.2HCl
Formula Weight Observed MW: 523.49
Assay Percent Range >98%
10

Eurofins Discoverx Dopamine, 10 mg. (92-1161)

Dopamine hydrochloride is an endogenous neurotransmitter with sympathomimetic properties that is a potent agonist of the dopamine receptors DRD1-5. Increases heartbeat and blood flow to the body's tissues, also playing a role in reward-motivated behavior. Addictive drugs tend to increase dopamine activity, and multiple nervous system diseases are associated with its dysfunction, including Parkinson's and schizophrenia. Precursor in noradrenalin and adrenalin biosynthesis. Provided as 10 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter,  PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.

ENCOMPASS_PREFERRED
11

TARGETMOL CHEMICALS INC DOPAMINE D2 RECEPTOR ANT 5MG
SDP

Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of dopamine D2 receptor (D2R) with sub-mM affinity. purity: 99%

ENCOMPASS_PREFERRED
12

Abcam Dopamine hydrochloride, Endogenous neurotransmitter 5g

Endogenous neurotransmitter

ENCOMPASS
13

Tocris Bioscience™ Pridopidine

Highly selective σ1 agonist

Target Sigma1 Receptor Agonists
CAS 346688-38-8
Purity 98%
Chemical Name or Material 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine
Recommended Storage Store at -20°C
Molecular Formula C15H23NO2S
14

Apexbio Technology LLC Dopamine HCl, 500mg Cas# 62-31-7
SDP

Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Other sizes are available. Please inqury us for quote.

ENCOMPASS_PREFERRED
15

Apexbio Technology LLC Dopamine HCl, 100mg Cas# 62-31-7
SDP

Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Other sizes are available. Please inqury us for quote.

ENCOMPASS_PREFERRED