Puromycin Dihydrochloride is an aminoglycoside antibiotic that is isolated from Streptomyces alboniger. Puromycin acts as a protein synthesis inhibitor by incorporating itself into a polypetide chain that has been growing, causing it to prematurely terminate. Puromycin's primary application is as a gene-selection antibiotic with an important role in gene-editing via CRISPR/Cas9.This puromycin reagent, which is in the form of hydrochloride salt, has antineoplastic, antitrypanosomal, and antimicrobial properties. It is important to keep Puromycin Dihydrochloride stored in a tightly closed container in a well-ventilated and dry area.CAS Number: 58-58-2Molecular Weight: 544.43 DaChemical Formula: C22H29N7O5 2HClSolubility: Soluble in water (50 mg/mL), ethanol (~1 mg/mL), DMSO (~13 mg/mL), DMF (~14 mg/mL), and PBS, pH 72 (~10 mg/mL)Storage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.