The 8x12 orange biohazard bag is ideal for processing biohazardous materials that require autoclaving prior to disposal. It is constructed from 2mil-thick rigid, high integrity polypropylene that can withstand 135C (275F) maximum autoclave temperature, resisting punctures, tears and leaks. It features a twist-tie closure that permits the bag to expand and vent steam during cooling. This model features an indicator statement Contents Have Been Autoclaved printed in a chemically active ink that darkens when autoclaving is complete, providing instant proof. It is sold in a case of 400.