Prenol lipids
Prenol lipids
Enzo Life Sciences AG-879 (5mg). CAS: 148741-30-4
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Betulinic acid (~95%) (500mg). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Enzo Life Sciences Docetaxel (5 mg). CAS: 114977-28-5
Docetaxel is taxane-type antineoplastic agent structurally similar to taxol. It reversibly binds to polymerized tubulin inhibiting depolymerization. It induces apoptosis in a large number of tumor cells and is a clinically important anticancer agent. Alternative name: Taxotere. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Betulinic acid (~95%) (1g). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Enzo Life Sciences AG-879 (25mg). CAS: 148741-30-4
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Tanshinone IIA (25mg). CAS: 568-72-9
Tanshinone IIA is a diterpenoid naphthoquinone found in the traditional Chinese medicine Tanshen (Salvia sp). It inhibits AP-1 activity by suppressing jun-fos-DNA complex formation (IC50=0.22 µM) and induces apoptosis in a variety of cell lines Purity: ≥93% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: +4°C.
