Custom Peptides
Custom Peptides
Genscript Corporation OVA Peptide (257-264)
This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Perkin Elmer US LLC Custom Standard HI 1A, 500 mL
Al @ 10 µg/mL, Mg @ 20 µg/mL Ca @ 32 µg/mL Cu, Fe, Pb, Zn @ 50 µg/mL B @ 1000 µg/mL, P @2000 µg/mL K @ 5000 µg/mL Na @10,000 µg/mL Matrix: 3% HNO3 (v/v) Volume: 500 mL
Revvity Health Sciences Inc AlphalISA Human C-peptide Detection Kit, Standard
AlphalISA Human C-peptide Detection Kit, Standard
Cayman Chemical ArachIdonyl SerInol 10mg
A KAT6A and KAT7 inhibitor (IC50s 17 and 30 nM respectively) selective for KAT6A and KAT7 over KAT5 (IC50 312 nM) reduces the viability of primary mouse LSCs MOLM-13 and OCI-AML-3 AML cells as well as decreases colony formation in patient-derived primary AML cells at 1 UM induces cell cycle arrest at the sub-G1 phase and apoptosis as well as decreases the levels of mRNA encoding HOXA7 in MOLM-13 cells at 1 UM reduces tumor volume weight and growth rate as well as decreases the acetylation at H3K14 H3K12 and H3K5 in tumor cell lysates in a PPC-1 prostate cancer mouse xenograft model
Cayman Chemical DIhomoLInolenIc AcId 10mg
A triantennary GalNAc ASGPR ligand has been used in the synthesis of siRNA-GalNAc conjUGates for RNA interference-mediated gene silencing in vitro and in mice
Cayman Chemical 5 Z 8 Z 11 ZEIcosatrIenoI 10mg
Source Recombinant human N-terminal His- and GST-tagged IGF2BP2 long isoform expressed in insect cells Amino acids 1-599 (full length) MW 94 kDa
Cayman Chemical TaurocholIc AcId 3sulfatS 10mg
A prodrUG form of C-82 cytotoxic to GES-1 gastric mucosal and HGC-27 MKN45 and AGS gastric cancer cells (IC50s 16.53 9.8 44.28 and 3.48 UM respectively) enhances lonidamine- or 2-DG-induced decreases in viability in CAL 27 SCC-25 and BICR 22 cells reduces hepatic fibrosis in a mouse model of CCl4-induced liver fibrosis at 0.4 mg/animal reduces the proliferation of CD4 or CD8 stem cell memory and central memory T cells in a rhesus macaque model of antiretroviral therapy-suppressed SIV infection at 10 or 20 mg/kg per day
Cayman Chemical N3hydroxyoctnoylLHomoser 10mg
A cationic quaternary ammonium lipid derivative of ALC-0315 LNPs containing Q1-ALC-0315 and ALC-0315 as a CLP and encapsulating mRNA encoding a luciferase reporter induce luciferase expression in the lungs and spleen in mice
Cayman Chemical Stearoyl EthnolamIde 10mg
An inhibitor of DCLK1 (IC50 17 nM) selective for DCLK1 over LRRK2 BRD4 and ERK5 (IC50s 7000 >10000 and 3350 nM respectively) reduces the number of cells in primary patient-derived pancreatic cancer organoids at 1 UM reduces plaque area and collagen levels in the aortic arches and serum levels of Tnf-a and Il-6 an ApoE-/- mouse model of high-fat diet-induced atherosclerosis at 10 mg/kg every other day
Cayman Chemical JWH 018 2naphthylN 2 2dI 10mg
An inhibitor of bacterialBglucuronidase (IC50 283 nM for the E. coli enzyme) inhibits wild-type but not 360-376 E. coliBglucuronidase at 100 UM reduces irinotecan-induced colonic epithelial damage and the number of bloody diarrheal events in a mouse model of chemotherapy-induced intestinal toxicity at 50 mg/kg
Cayman Chemical ArachIdonyl m-NItronIlIn 10mg
An inhibitor of Cdk9/cyclin T1 Cdk1/cyclin B and Cdk2/cyclin A complexes (Kis 4 4 and 3 nM respectively) selective for these complexes over the Cdk7/cyclin H complex (Ki 91 nM) cytotoxic to HCT116 cells (GI50 <10 nM) induces apoptosis in COLO 205 HCT116 HT-29 and KM12 cells at 0.25 or 1 UM reduces the levels of Bcl-2 cyclin D1 and Mcl-1 as well as decreases the mitochondrial membrane potential in HCT116 cells at 0.25 UM decreases tumor volume in an HCT116 mouse xenograft model at 100 mg/kg every three days
Cayman Chemical 1 2bIs heptnoylthIo GlycR 10mg
A p62 antagonist (IC50 31.18 nM for the human receptor) decreases the soluble fraction of p62 in MM.1S cells at1.5 UM increases the levels of polyubiquitinated proteins in MM.1S cells at 200 nM induces apoptosis in MM.1S at 100 nM decreases the survival of CD138 cells but not CD138- cells in primary plasma cells derived from patients with multiple myeloma at 50 to 400 nM reduces the viability of tumor tissue samples isolated from ten PDX mouse models of colorectal cancer (IC50s 113-1220 nM) reduces tumor volume in an HCT116 mouse xenograft model at 8 or 12 mg/kg twice per week
Cayman Chemical JWH 018 2naphthylN 1 2dI 10mg
An inhibitor of bacterialBglucuronidase (IC50 283 nM for the E. coli enzyme) inhibits wild-type but not 360-376 E. coliBglucuronidase at 100 UM reduces irinotecan-induced colonic epithelial damage and the number of bloody diarrheal events in a mouse model of chemotherapy-induced intestinal toxicity at 50 mg/kg