Ligand for TLR7 and TLR8. R-848 is a selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Potent antitumor and antiviral compound. Stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 upregulation. Alternative Name: 4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol. S 28463, Resiquimod, Formula: C17H22N4O2. MW: 314.4. CAS Number: 144875-48-9. Purity: ≥98% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in DMSO, dichloromethane, 100% or 5% methanol; poorly soluble in acetonitrile or ethyl acetate. Long Term Storage: -20°C