CAS #75-76-3 Si(CH₃)₄
Boiling point: 26.6-26.7°C
An organo-silicon compound, tetramethylsilane (TMS) is an ideal solvent for tissue drying for scanning electron microscopy. It is chemically inert, has as low boiling point of 26.6°C (lower than acetone, diethyl ether and 1,2-epoxy propane), and is soluble in most organic solvents but insoluble in water. These properties of TMS result in excellent tissue surface details.
For details please see Dey, Sudip. Et al. (1989). A new rapid method of air-drying for scanning electron microscopy using tetramethylsilane. J. of Microscopy, Vol 156, pp. 259-261.