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Tocris Bioscience™ Rhosin hydrochloride

Rho GTPase inhibitor

$651.92

Specifications

Purity >98%
Inhibitors Rho GTPase Inhibitors
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-035-0R
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Tocris Bioscience™
5003/50 		50 mg
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50-031-0R
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Tocris Bioscience™
5003/10 		10 mg N/A N/A N/A
Description

Description

Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro. Also induces neurite outgrowth in synergy with NGF.
Specifications

Specifications

>98%
Rho GTPase Inhibitors
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