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Tocris Bioscience™ Rhosin hydrochloride

Rho GTPase inhibitor

Supplier:  Tocris Bioscience™ 5003/50

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Catalog No. 50-035-0R


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Description

Description

Rhosin hydrochloride is a Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro. Also induces neurite outgrowth in synergy with NGF.
Specifications

Specifications

>98%
Rhosin hydrochloride
Rho GTPase Inhibitors
50 mg
394.86
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