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  5. Tocris Bioscience™ LSN 2463359

Tocris Bioscience™ LSN 2463359

Potent and selective positive allosteric modulator at mGlu5

$212.50 - $862.50

Specifications

Purity >99%
Product Type LSN 2463359
Molecular Weight (g/mol) 265.31
Inhibitors LSN 2463359
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
52-751-0
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Tocris Bioscience™
5275/10 		10 mg
Each for $212.50
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52-755-0
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Tocris Bioscience™
5275/50 		50 mg
Each for $862.50
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Description

Description

Potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). Has no activity at mGlu1-4, mGlu8 and GABAB receptors. Reverses methylazoxymethanol acetate (MAM)-induced deficits in reversal learning memory and normalizes SDZ 220-581 and RO 63-1908 -induced alterations in instrumental responses in rat models. Promotes wakefulness in vivo. Brain penetrant and orally active.
Specifications

Specifications

>99%
LSN 2463359
265.31
LSN 2463359
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