Invitrogen™ GM-CSF Mouse ELISA Development Kit (ABTS), PeproTech®, PeproTech®

ELISA

Supplier:  Invitrogen™ 900K55

Catalog No. 900-K55

Description

GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).

Specifications

• Accession Number: P01587
• Gene ID (Entrez): 12981
• Quantity: 10 x 96 Tests
• Storage Requirements: Refer to product documentation for component specific storage temperature.

• Product Type: ELISA
• Gene Symbol: CSF2
• Regulatory Status: RUO
• Target: Mouse