Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Catalog Number	Mfr. No.	Quantity
PIA39267	Thermo Scientific™ A39267	10 x 2 mg
PI21655	Thermo Scientific™ 21655	50 mg
PI21555	Thermo Scientific™ 21555	1 g

Description

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Highlights:

• Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
• “Fix” protein interactions to allow identification of weak or transient protein interactions
• Protein crosslinking to create bioconjugates via single-step reactions
• Crosslink oriented antibodies to Protein A or G agarose
• Immobilize proteins onto amine-coated surfaces

Specifications

• Cleavable: No