Thermo Scientific Chemicals Caspase-3 Inhibitor III

Description

A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 -M to examine the role of caspase-3-dependent apoptosis

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 285570-60-7
• Molecular Formula: C21H31ClN4O11
• Synonym: Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone

• Quantity: 1 mg
• Description: Off-white to brown
• Content And Storage: -30°C to -10°C
• For Use With (Application): A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 →M to examine the role of caspase-3-dependent apoptosis
• Formula Weight: 550.94
• Solubility: Soluble in DMSO
• Form: Powder
• InChI Key: ATNOUPFYBMVFLD-UHFFFAOYNA-N
• SMILES: CC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(=O)NC(CC(O)=O)C(=O)CCl
• IUPAC Name: 3-{2-[4-carboxy-2-(3-carboxy-2-acetamidopropanamido)butanamido]-3-methylbutanamido}-5-chloro-4-oxopentanoic acid
• Molecular Weight (g/mol): 550.95

Safety and Handling

Recommended Storage

Store at -20°C

SDS

RUO – Research Use Only