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Tocris Bioscience™ AZD 7762 hydrochloride
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2
$322.48 - $1340.96
Specifications
Purity | >98% |
---|---|
Product Type | AZD 7762 hydrochloride |
Molecular Weight (g/mol) | 398.88 |
Inhibitors | AZD 7762 hydrochloride |
Description
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5 nM for both kinases); displays at least >10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo. Also improves efficiency of CRISPR-Cpf1-mediated genome editing in hPSC lines (2.7-fold at 1 μM).Specifications
>98% | |
AZD 7762 hydrochloride | |
398.88 | |
AZD 7762 hydrochloride |
For Research Use Only
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