High activity, high purity CD40L protein for co-stimulatory activation of an immune response. MEGACD40L. in vivo. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations (Prod. No. ALX-850-064). Alternative name: CD40L, CD154, TNFSF 5, gp39. MW: ~38kDa. Concentration: 0.1mg/ml after reconstitution. Endotoxin content: ≤0.01EU/µg purified protein (LAL test; Cape Cod Associates). Purity: ≥90% (SDS-PAGE). Formulation: Lyophilized. Contains PBS. Source: Produced in CHO cells. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG-tag. Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. UniProt: P29965 (human CD40L), Q60994 (mouse Adiponectin). Handling: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. Long Term Storage: -20°C