Active component of propolis from honeybee hives, known to have anti-mitogenic, anti-carcinogenic, anti-inflammatory, and immunomodulatory properties. Potent and specific inhibitor of NF-κB activation, induced by TNF-α (ALX-522-008 (human) or ALX-522-009 (mouse)), PMA (BML-PE160) and other inflammatory agents. Exhibits inhibitory activity against HIV-1 integrase (IC50=7µM). Suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities. Induces apoptosis. Alternative name: CAPE, Phenethyl caffeiate, Caffeic acid phenethyl ester. Formula: C17H16O4. MW: 284.3. Purity: ≥97% (HPLC). Solubility: 10mg/ml soluble in DMSO, 100% ethanol, methanol, acetone or acetonitrile; insoluble in water. Long Term Storage: -20°C.