DRB is a potent and specific inhibitor of casein kinase II (CKII, IC50~6 µM). It has been used to inhibit RNA polymerase II mediated-transcription which may be dependent on CKII and its interaction with ATF-1. Alternative name: DRB, 5,6-Dichlorobenzimidazole riboside. Purity: ≥97% (TLC). Solubility: Soluble in DMSO (20mg/ml), 100% ethanol, and dimethyl formamide (100mM). Long Term Storage: -20°C.