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Xanthohumol, Tocris Bioscience™

Catalog No. 468610
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

p97 ATPase (VCP) inhibitor

p97 ATPase (VCP) inhibitor. Binds to the N domain of p97, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC50 = 50.3 μM).

Chemical Identifiers

CAS 6754-58-1
Molecular Formula C21H22O5
Molecular Weight (g/mol) 354.402
InChI Key ORXQGKIUCDPEAJ-YRNVUSSQSA-N
Synonym xanthohumol, 1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-en-1-yl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, unii-t4467yt1nt, 2',4,4'-trihydroxy-6'-methoxy-3'-prenylchalcone, 1-2,4-dihydroxy-6-methoxy-3-3-methyl-2-butenyl phenyl-3-4-hydroxyphenyl-2-propen-1-one, 2e-1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-en-1-yl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, e-1-2,4-dihydroxy-6-methoxy-3-3-methyl-2-butenyl phenyl-3-4-hydroxyphenyl propenone, e-1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-enyl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, xanthohumol from hop humulus lupulus, 2',4,4'-trihydroxy-3'-prenyl-6'-methoxychalcone
PubChem CID 639665
ChEBI CHEBI:66331
IUPAC Name (E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
SMILES CC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C

Specifications

Quantity 10 mg
Formula Weight 354.4
Percent Purity >98%
Chemical Name or Material Xanthohumol

Safety and Handling

Recommended Storage Store at +4°C
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