(+/-)-Verapamil hydrochloride, 99+%, Thermo Scientific Chemicals

Description

 

±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. It is also a calcium channel-blocker. It acts by inhibiting the slow channel entry of calcium into the cell. It acts by plugging up the channels and limiting the entry of calcium into both smooth muscle cells of arteriolar walls and the cardiac muscle cells at higher doses.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. It is also a calcium channel-blocker. It acts by inhibiting the slow channel e

Specifications

Chemical Identifiers

• CAS: 152-11-4
• Molecular Formula: C27H39ClN2O4
• Molecular Weight (g/mol): 491.069
• MDL Number: MFCD00055208
• InChI Key: DOQPXTMNIUCOSY-UHFFFAOYSA-N
• Synonym: verapamil hydrochloride, verapamil hcl, manidon, calcan hydrochloride, cardibeltin, cardiabeltin, cardioprotect, veroptinstada, calaptin, caveril
• PubChem CID: 62969
• IUPAC Name: 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
• SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

• Melting Point: 138°C to 141°C
• Color: White
• Quantity: 1 g
• UN Number: UN2811
• Beilstein: 3647093
• Merck Index: 14,9950
• Solubility Information: Soluble in water; Also soluble in ethanol or methanol
• Formula Weight: 491.07
• Percent Purity: ≥99%
• Physical Form: Powder
• Chemical Name or Material: (+/-)-Verapamil hydrochloride

Safety and Handling

Hazard Category	H301+H311+H331
Hazard Statement	GHS H Statement H301-H311-H331 Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled.
Precautionary Statement	P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P314-P330-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	205-800-5
RTECSNumber	YV8320000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only