TrkA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA595139

Catalog No. PIPA595139

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL.

NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Specifications

• Antigen: TrkA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ntrk1
• Gene Alias: C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18211, 59109
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
• Gene Accession No.: P35739, Q3UFB7
• Gene Symbols: Ntrk1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse TrkA (71-90aa LYVENQQHLQRLEFEDLQGL).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG