Trifluoromethanesulfonic acid, 98+%, Thermo Scientific Chemicals

Description

Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.

Solubility
Miscible with water, dimethyl sulfoxide, dimethyl formamide and acetonitrile.

Notes
Hygroscopic. Incompatible with strong oxidizing agents, strong bases, water and metals.

Specifications

Chemical Identifiers

• CAS: 1493-13-6
• Molecular Formula: CHF3O3S
• Molecular Weight (g/mol): 150.07
• MDL Number: MFCD00007514
• InChI Key: ITMCEJHCFYSIIV-UHFFFAOYSA-N
• Synonym: triflic acid, perfluoromethanesulfonic acid, trifluoromethanesulphonic acid, tfmsa, trifluoromethane sulfonic acid, tfoh, methanesulfonic acid, trifluoro, hotf, trifluoromethylsulfonic acid, trimsylate
• PubChem CID: 62406
• ChEBI: CHEBI:48511
• IUPAC Name: trifluoromethanesulfonic acid
• SMILES: OS(=O)(=O)C(F)(F)F

• Melting Point: -40°C
• Density: 1.708
• Boiling Point: 161°C to 162°C
• Flash Point: None
• Odor: Pungent
• Refractive Index: 1.327
• Linear Formula: CF₃SO₃H
• Quantity: 50 g
• UN Number: UN3265
• Beilstein: 1812100
• Sensitivity: Hygroscopic
• Merck Index: 14,9676
• Solubility Information: Miscible with water,dimethyl sulfoxide,dimethyl formamide and acetonitrile.
• Formula Weight: 150.07
• Percent Purity: ≥98%
• Chemical Name or Material: Trifluoromethanesulfonic acid

Safety and Handling

Hazard Category	H290-H302-H314-H335
Hazard Statement	GHS H Statement H314-H318-H302-H335 Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed. May cause respiratory irritation.
Precautionary Statement	P234-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P390-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	216-087-5
RTECSNumber	PB2771000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only