Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals

Description

The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and ceramic compounds. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. It finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 76-05-1
• Molecular Formula: C2HF3O2
• Molecular Weight (g/mol): 114.02
• MDL Number: MFCD00004169
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N
• Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
• PubChem CID: 6422
• ChEBI: CHEBI:45892
• IUPAC Name: 2,2,2-trifluoroacetic acid
• SMILES: OC(=O)C(F)(F)F

• Melting Point: -15°C
• Boiling Point: 72°C to 73°C
• Color: Colorless
• Assay Percent Range: >99.5%
• UN Number: 2699
• Beilstein: 742035
• Solubility Information: Miscible with water,ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
• Formula Weight: 114.02
• Grade: HPLC
• Density: 1.48
• Quantity: 4 x 500 mL
• Odor: Pungent
• Physical Form: Liquid
• Refractive Index: 1.284
• Sensitivity: Hygroscopic
• Vapor Pressure: 8mm Hg at 20°C
• Chemical Name or Material: Trifluoroacetic Acid, Water 0.1%

Safety and Handling

Hazard Category	H290-H314-H332-H335
Precautionary Statement	P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c
DOTInformation	DOT Class: 8, Packaging Group: I
EINECSNumber	200-929-3
RTECSNumber	AJ9625000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only