Tri-tert-butylphosphonium tetrafluoroborate, 97%, Thermo Scientific Chemicals

Description

Tri-tert-butylphosphonium tetrafluoroborate is a ligand used in the palladium-catalyzed enantioselective alfa-arylation of N-boc-pyrrolidine. It is also used with a palladium(0)-15-membered, triolefinic, macrocyle in Suzuki cross-coupling reactions of aryl bromides and chlorides. Further, it is used in the Heck coupling of vinyl tosylates with olefins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tri-tert-butylphosphonium tetrafluoroborate is a ligand used in the palladium-catalyzed enantioselective alfa-arylation of N-boc-pyrrolidine. It is also used with a palladium(0)-15-membered, triolefinic, macrocyle in Suzuki cross-coupling reactions of aryl bromides and chlorides. Further, it is used in the Heck coupling of vinyl tosylates with olefins.

Solubility
Soluble in methylene chloride and chloroform. Slightly soluble in terahydro furan. Insoluble in hexane, toluene and water.

Notes
Incompatible with strong oxidizing agents and halogens.

Specifications

Chemical Identifiers

• CAS: 131274-22-1
• Molecular Formula: C12H28BF4P
• Molecular Weight (g/mol): 290.13
• MDL Number: MFCD04039975
• InChI Key: YTJUCJAUJCXFTN-UHFFFAOYSA-O
• Synonym: tri-tert-butylphosphonium tetrafluoroborate, t-bu 3ph bf4, tri-t-butylphosphonium tetrafluoroborate, fluoroboric acid tri-tert-butylphosphine adduct, tri-tert-butylphosphanium tetrafluoroborate, tbu3p hbf4, ttbp hbf4, t-bu3p hbf4, tbu 3p hbf4, acmc-20a4f9
• PubChem CID: 2734635
• IUPAC Name: tritert-butylphosphanium;tetrafluoroborate
• SMILES: F[B-](F)(F)F.CC(C)(C)[PH+](C(C)(C)C)C(C)(C)C

• Melting Point: 266°C to 267°C
• Quantity: 5 g
• Beilstein: 8813613
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in methylene chloride and chloroform. Slightly soluble in terahydro furan. Insoluble in hexane,toluene and water.
• Formula Weight: 290.13
• Percent Purity: 97%
• Chemical Name or Material: Tri-tert-butylphosphonium tetrafluoroborate

Safety and Handling

Hazard Category	H302+H312+H332-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only