Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyridopyrimidines
  7. 233710

Trequinsin hydrochloride, Tocris Bioscience™

Catalog No. 233710
Click to view available options
Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Extremely potent inhibitor of PDE3

Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.

Chemical Identifiers

CAS 78416-81-6
Molecular Formula C24H28ClN3O3
Molecular Weight (g/mol) 441.96
MDL Number MFCD01076563
InChI Key DTCZZBVPTHVXFA-UHFFFAOYSA-N
Synonym trequinsin hydrochloride, trequinsin, hydrochloride, dsstox_cid_25806, dsstox_rid_81144, dsstox_gsid_45806, 4h-pyrimido 6,1-a isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-2,4,6-trimethylphenyl imino-, monohydrochloride, 9,10-dimethoxy-2-mesitylimino-3-methyl-2,3,6,7-tetrahydro-4h-pyrimido-6,1-a-isoquinolin-4-one, hcl, trequinsin hcl, trequinsinhydrochlorid, c24h27n3o3.hcl
PubChem CID 3060974
IUPAC Name hydrogen 9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2H,3H,4H,6H,7H-pyrimido[4,3-a]isoquinolin-4-one chloride
SMILES [H+].[Cl-].COC1=CC2=C(C=C1OC)C1=CC(=NC3=C(C)C=C(C)C=C3C)N(C)C(=O)N1CC2

Specifications

Quantity 10 mg
Formula Weight 441.95
Percent Purity >97%
Chemical Name or Material Trequinsin hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.