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  7. TRAM 34, Tocris Bioscience™

TRAM 34, Tocris Bioscience™

Catalog No. 294650
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and highly selective KCa3.1 channel blocker

Potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Chemical Identifiers

CAS 289905-88-0
Molecular Formula C22H17ClN2
Molecular Weight (g/mol) 344.842
InChI Key KBFUQFVFYYBHBT-UHFFFAOYSA-N
Synonym tram-34, 1-2-chlorophenyl diphenylmethyl-1h-pyrazole, tram 34, 1-2-chlorophenyl-diphenylmethyl pyrazole, surecn41130, d03yvq, d05rlr, tram hplc , solid, 1-2-chlorophenyl-diphenyl-methyl pyrazole
PubChem CID 656734
ChEBI CHEBI:34990
IUPAC Name 1-[(2-chlorophenyl)-diphenylmethyl]pyrazole
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4

Specifications

Quantity 50 mg
Formula Weight 344.84
Percent Purity >99%
Chemical Name or Material TRAM 34

Safety and Handling

Recommended Storage Store at +4°C
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