Thiosalicylic acid, 98%, Thermo Scientific Chemicals

Description

Thiosalicylic acid acts as a trapping agent, which is useful in the desulfenylation of 3-indolyl sulfides. It is used to prepare macrocyclic diamides by condensation with diamines. Further, it is used as a precursor to drug, which finds application for the treatment of atherosclerosis and melanoma. In addition to this, it is involved in the preparation of vaccine preservative thiomersal and thioindigo dyestuff.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiosalicylic acid acts as a trapping agent, which is useful in the desulfenylation of 3-indolyl sulfides. It is used to prepare macrocyclic diamides by condensation with diamines. Further, it is used as a precursor to drug, which finds application for the treatment of atherosclerosis and melanoma. In addition to this, it is involved in the preparation of vaccine preservative thiomersal and thioindigo dyestuff.

Solubility
Soluble in dimethyl sulfoxide, alcohol and ether. Slightly soluble in water, ethanol and alkanes.

Notes
Air and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 147-93-3
• Molecular Formula: C7H6O2S
• Molecular Weight (g/mol): 154.183
• MDL Number: MFCD00004836
• InChI Key: NBOMNTLFRHMDEZ-UHFFFAOYSA-N
• Synonym: thiosalicylic acid, 2-mercaptobenzoic acid, o-mercaptobenzoic acid, 2-thiosalicylic acid, o-thiosalicylic acid, 2-carboxythiophenol, o-benzoic acid thiol, o-carboxythiophenol, o-sulfhydrylbenzoic acid, benzoic acid, 2-mercapto
• PubChem CID: 5443
• ChEBI: CHEBI:59124
• IUPAC Name: 2-sulfanylbenzoic acid
• SMILES: C1=CC=C(C(=C1)C(=O)O)S

• Melting Point: 165°C to 168°C
• Beilstein: 508507
• Merck Index: 149360
• Solubility Information: Soluble in dimethyl sulfoxide,alcohol and ether. Slightly soluble in water,ethanol and alkanes.
• Formula Weight: 154.19
• Percent Purity: 98%
• Density: 1.49
• Quantity: 250 g
• Odor: Stench
• Sensitivity: Air and light sensitive
• Chemical Name or Material: Thiosalicylic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	205-704-3
RTECSNumber	DH3325000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only