Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organosulfur Compounds
  6. Thioureas
  7. Thioperamide, Tocris Bioscience™

Thioperamide, Tocris Bioscience™

Catalog No. 064450
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

H3 antagonist; also H4 inverse agonist

Potent histamine H3 and H4 antagonist/inverse agonist. Ki values are 25 and 27 nM for human recombinant H3 and H4 receptors respectively. Blocks eosinophil shape change (IC50 = 1.4 μM) and chemotaxis (IC50 = 519 nM) induced by histamine. Freely crosses the blood-brain barrier.

Chemical Identifiers

CAS 106243-16-7
Molecular Formula C19H28N4O4S
Molecular Weight (g/mol) 408.517
InChI Key WUYMIKDBRCCYGE-UHFFFAOYSA-N
Synonym 1-piperidinecarbothioamide, n-cyclohexyl-4-1h-imidazol-4-yl-, 2z-2-butenedioate 1:1
PubChem CID 53393972
IUPAC Name but-2-enedioic acid;N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
SMILES C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3.C(=CC(=O)O)C(=O)O

Specifications

Quantity 50 mg
Formula Weight 292.44
Percent Purity >99%
Chemical Name or Material Thioperamide

Safety and Handling

Recommended Storage Store at -20°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.