Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%

Description

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.

Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 298-93-1
• Molecular Formula: C18H16BrN5S
• Molecular Weight (g/mol): 414.33
• MDL Number: MFCD00011964,MFCD00066662
• InChI Key: AZKSAVLVSZKNRD-UHFFFAOYSA-M
• Synonym: thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i
• PubChem CID: 64965
• ChEBI: CHEBI:53233
• IUPAC Name: 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide
• SMILES: [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1

• Melting Point: ∽195°C (decomposition)
• Odor: Odorless
• Quantity: 5 g
• Beilstein: 3825277
• Sensitivity: Air, light, and moisture sensitive
• Solubility Information: Soluble in water,ethanol,2-methoxyethanol and phosphate buffered saline.
• Formula Weight: 414.33
• Percent Purity: 98%
• Chemical Name or Material: Thiazolyl Blue tetrazolium bromide

Safety and Handling

Hazard Category	H315-H319-H335-H341
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
EINECSNumber	206-069-5
RTECSNumber	XF8060000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only