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Tocris Bioscience™ Thalidomide
Binds cereblon; also TNF-α synthesis inhibitor
Supplier: Tocris Bioscience™ 0652/100
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Description
Thalidomide is a selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Anti-inflammatory; promotes T-cell activation. Predicted to reduce cytokine release in SARS-CoV-2 infection. Also binds cereblon, inhibiting ubiquitin ligase activity. Teratogenic and sedative-hypnotic. Promotes degradation of transcription factor SALL4.Specifications
99% | |
50-35-1 | |
100 mg | |
M.W. (Observed): 258.23 |
N-(2,6-dioxo-3-piperidinyl)phthalimide | |
Room Temperature | |
Thalidomide | |
Thalidomide |
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