Tetronic acid, 96%, Thermo Scientific Chemicals

Description

Tetronic acid is used as a precursor of a variety of substituted and ring-fused furans and butenolides. It is an acidic building block for heterocyclic compounds for medicinal applications. It is used for selective O-alkyaltion reactions involving cesium fluoride. It is also used to prepare 3H-furo[3,4-b]quinolin-1-one by reacting with 2-amino-benzaldehyde.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tetronic acid is used as a precursor of a variety of substituted and ring-fused furans and butenolides. It is an acidic building block for heterocyclic compounds for medicinal applications. It is used for selective O-alkyaltion reactions involving cesium fluoride. It is also used to prepare 3H-furo[3,4-b]quinolin-1-one by reacting with 2-amino-benzaldehyde.

Solubility
Soluble in water, dimethyl sulfoxide, acetonitrile and alcohol.

Notes
Incompatible with strong oxidizing agents and strong alkalis (bases).

Specifications

Chemical Identifiers

• CAS: 541-57-1
• Molecular Formula: C4H4O3
• Molecular Weight (g/mol): 100.07
• MDL Number: MFCD00052187
• InChI Key: JZQBAGOECGRTSA-UHFFFAOYSA-N
• SMILES: OC1=CC(=O)OC1

• Melting Point: ∼140°C (decomposition)
• Assay Percent Range: 96%
• Beilstein: 108442
• Synonym: 4-hydroxyfuran-2 5h-one, 4-hydroxy-2,5-dihydrofuran-2-one, 4-hydroxy-2 5h-furanone, 2 5h-furanone, 4-hydroxy, 4-hydroxy-5h-furan-2-one, 5-hydroxyfuran-3-one, 5-hydroxyfuran-3 2h-one, pubchem21770, acmc-209xna, tetronic acid 5g
• Solubility Information: Soluble in water,dimethyl sulfoxide,acetonitrile and alcohol.
• IUPAC Name: 3-hydroxy-2H-furan-5-one
• PubChem CID: 54683813
• Formula Weight: 100.07
• Percent Purity: 96%
• Quantity: 25 g
• Chemical Name or Material: Tetronic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	208-785-3
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only