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TC-S 7005, Tocris Bioscience™

Catalog No. 4459
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective PLK2 inhibitor

Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.

Chemical Identifiers

CAS 1082739-92-1
Molecular Formula C21H17N3O3
Molecular Weight (g/mol) 359.385
InChI Key DAAGOCSHXCDWDY-ZDUSSCGKSA-N
Synonym 2-amino-isoxazolopyridine, 9, 3-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl-isoxazolo 5,4-c pyridin-5-amine, 3-2h-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl pyrido 4,3-d 1,2 oxazol-5-amine
PubChem CID 24971422
IUPAC Name 3-(1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-[1,2]oxazolo[5,4-c]pyridin-5-amine
SMILES CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5

Specifications

Color Cream
Quantity 10 mg
Formula Weight 359.38
Percent Purity >98%
Physical Form Solid
Chemical Name or Material TC-S 7005

Safety and Handling

Recommended Storage Store at +4°C
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