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TB 21007, Tocris Bioscience™

Catalog No. 290550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

α5-selective GABAA inverse agonist

GABAA receptor inverse agonist selective for the α5-subtype (Ki values are 1.6, 16, 20 and 20 nM for α5, α2, α1 and α3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.

Chemical Identifiers

CAS 207306-50-1
Molecular Formula C15H17NO2S3
Molecular Weight (g/mol) 339.486
InChI Key QILRYFCEXLFIDS-UHFFFAOYSA-N
Synonym chembl17603, 3-2-hydroxyethyl sulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one, 6,7-dihydro-3-2-hydroxyethyl thio-6,6-dimethyl-1-2-thiazolyl-benzo c thiophen-4 5h-one, 1-2-thiazolyl-3-2-hydroxyethylthio-6,6-dimethyl-6,7-dihydrobenzo c thiophene-4 5h-one, 3-2-hydroxy-ethylsulfanyl-6,6-dimethyl-1-thiazol-2-yl-6,7-dihydro-5h-benzo c thiophen-4-one, 3-2-hydroxyethylsulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one
PubChem CID 6918633
IUPAC Name 3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
SMILES CC1(CC2=C(SC(=C2C(=O)C1)SCCO)C3=NC=CS3)C

Specifications

Quantity 50 mg
Formula Weight 339.5
Percent Purity >99%
Chemical Name or Material TB 21007

Safety and Handling

Recommended Storage Store at +4°C
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