Squalene, MP Biomedicals™

Description

Functions as the biochemical precursor to the whole family of steroids. Squalene, MP Biomedicals is an isoprenoid compound that is structurally similar to beta-carotene and is an intermediate metabolite in the synthesis of cholesterol. Squalene is not ver

• Functions in the skin as a quencher of singlet oxygen, protecting human skin surface from lipid peroxidation due to exposure to UV and other sources of ionizing radiation
• Supplementation in mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner
• May act as a “sink” for highly lipophilic xenobiotics; since it is a nonpolar substance, it has a higher affinity for un-ionized drugs
• Supplementation can reduce cholesterol and triglyceride levels; it might be a useful addition to potentiate the effects of some cholesterol-lowering drugs
• The primary therapeutic use of squalene currently is as an adjunctive therapy in a variety of cancers

Specifications

Chemical Identifiers

• CAS: 111-02-4
• Molecular Formula: C30H50
• Molecular Weight (g/mol): 410.73
• InChI Key: YYGNTYWPHWGJRM-AAJYLUCBSA-N
• Synonym: squalene, trans-squalene, spinacene, supraene, all-trans-squalene, 2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, e,e,e,e-squalene, unii-7qwm220fjh, 7qwm220fjh, spinacen
• PubChem CID: 638072
• ChEBI: CHEBI:15440
• IUPAC Name: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene
• SMILES: CC(=CCCC(=CCCC(=CCCC=C(C)CCC=C(C)CCC=C(C)C)C)C)C

• Melting Point: -75°C (literature)
• Density: 0.858g/mL at 25°C (Lit.)
• Boiling Point: 285°C (25mm (literature))
• Refractive Index: n20/D 1.494 (Lit.)
• Quantity: 1 L
• Formula Weight: 410.7
• Percent Purity: ≥98%
• Physical Form: Liquid

Safety and Handling

Recommended Storage

Room Temperature (15–30°C).