Sotalol hydrochloride, 98%, Thermo Scientific Chemicals

Description

Potent beta adrenergic antagonist

Sotalol hydrochloride is used as a potent beta adrenergic antagonist, prolongs the action potential and increases the refractory period. Sotalol hydrochloride is also considered a non-selective β blocker and a potassium channel blocker with an IC50 of 43 μM.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sotalol hydrochloride is used as a potent beta adrenergic antagonist, prolongs the action potential and increases the refractory period. Sotalol hydrochloride is also considered a non-selective β blocker and a potassium channel blocker with an IC50 of 43 µM.

Solubility
Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 959-24-0
• Molecular Formula: C12H21ClN2O3S
• Molecular Weight (g/mol): 308.82
• MDL Number: MFCD00242937
• InChI Key: VIDRYROWYFWGSY-UHFFFAOYNA-N
• Synonym: sotalol hydrochloride, sotalol hcl, betapace, betapace af, sotacor, sotalex, berlex, mead johnson 1999, sorine
• PubChem CID: 66245
• ChEBI: CHEBI:9207
• IUPAC Name: hydrogen N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide chloride
• SMILES: [H+].[Cl-].CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1

• Color: White
• Quantity: 100 mg
• Merck Index: 14,8728
• Solubility Information: Soluble in phosphate buffered saline,DMSO,ethanol,water,and methanol.
• Formula Weight: 308.82
• Percent Purity: 98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Sotalol hydrochloride

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	213-496-0
RTECSNumber	PB0826000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only