Thermo Scientific Pierce™ Pierce™ SM(PEG)12, No-Weigh™ Format

Thermo Scientific™ Pierce™ SM(PEG)12 is hetero-bifunctional crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules.

Supplier:  Thermo Scientific Pierce™ A35398

Catalog No. PIA35398

Description

Thermo Scientific No-Weigh products are specialty reagents provided in a pre-aliquoted format. The pre-weighed packaging helps prevent loss of reagent reactivity and contamination over time by minimizing repetitive opening and closing of vial. The format enables use of fresh vial of reagent each time, eliminating the hassle of weighing small amounts of reagents and reducing concerns over reagent stability.

• Reactive groups: NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups
• Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
• Polyethylene glycol spacer arms help maintain conjugate solubility
• Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
• PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
• Ideal for performing controlled, two-step protein conjugations

Specifications

• Chemical Reactivity: Amine-Sulfhydryl
• Description: BS(PEG)5
• PEGylated: Yes
• Content And Storage: Upon receipt store desiccated at -20°C.
• Shipping Condition: Wet Ice
• Labeling Method: Chemical Labeling
• Reactive Moiety: Maleimide, NHS Ester
• Form: Solid
• Solubility: Water
• Water-Soluble: Yes

• Cleavable: No
• Molecular Weight (g/mol): 532.5
• Spacer Arm Length: 53.4 Å
• Cell-Permeable: No
• Product Line: No-Weigh™, Pierce™
• Crosslinker Type: Heterobifunctional
• Spacer: Long (>30 Å)
• Quantity: 10 x 1 mg
• Format: Standard, Single use
• Product Type: Crosslinker

For Research Use Only