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  7. SKF 97541, Tocris Bioscience™

SKF 97541, Tocris Bioscience™

Catalog No. 037950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly potent GABAB agonist; also GABAA-ρ antagonist

SKF 97541 is a potent GABAB agonist (EC50 = 50 nM). SKF 97541 depresses striatal synaptic potentials and hyperpolarizes nigral neurons (EC50 values = 92 nM and 150 nM, respectively). SKF 97541 shows antidepressant effects in animal models and is also a GABAA-ρ antagonist.

Chemical Identifiers

CAS 127729-35-5
Molecular Formula C4H12NO2P
Molecular Weight (g/mol) 137.119
InChI Key NHVRIDDXGZPJTJ-UHFFFAOYSA-N
Synonym 3-apmpa, 3-aminopropyl methyl phosphinic acid, skf 97541 hydrochloride, 3-aminopropyl methylphosphinic acid, phosphinic acid, 3-aminopropyl methyl, 3-ammoniopropyl methylphosphinate, tocris-0379, lopac-a-196
PubChem CID 5230
IUPAC Name 3-aminopropyl(methyl)phosphinic acid
SMILES CP(=O)(CCCN)O

Specifications

Quantity 50 mg
Formula Weight 137.12
Percent Purity >98%
Chemical Name or Material SKF 97541

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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