(S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%, Thermo Scientific Chemicals

Description

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid is used as a building block for pharmaceuticals and asymmetric synthesis. It Is also used as a resolving agent for chiral bases and in an efficient synthesis of quinolizidine and indolizidine alkaloids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-2-Pyrrolidinone-5-carboxylic acid is used as a building block for pharmaceuticals and asymmetric synthesis. It Is also used as a resolving agent for chiral bases and in an efficient synthesis of quinolizidine and indolizidine alkaloids.

Solubility
Soluble in water (10-15% at 20°C), alcohol, acetone, dimethyl sufoxide and methanol.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 98-79-3
• Molecular Formula: C5H7NO3
• Molecular Weight (g/mol): 129.12
• MDL Number: MFCD00005272
• InChI Key: ODHCTXKNWHHXJC-UHFFFAOYNA-N
• Synonym: l-pyroglutamic acid, pyroglutamic acid, pidolic acid, 5-oxo-l-proline, h-pyr-oh, 5-oxoproline, s-5-oxopyrrolidine-2-carboxylic acid, 2s-5-oxopyrrolidine-2-carboxylic acid, l-5-oxoproline, l-proline, 5-oxo
• PubChem CID: 7405
• ChEBI: CHEBI:18183
• SMILES: OC(=O)C1CCC(=O)N1

• Melting Point: 158°C to 162°C
• Quantity: 500 g
• Beilstein: 82132
• Merck Index: 14,8001
• Solubility Information: Soluble in water (10-15% at 20°C),alcohol,acetone,dimethyl sufoxide and methanol.
• Optical Rotation: −10.5° (c=5 in Water)
• IUPAC Name: 5-oxopyrrolidine-2-carboxylic acid
• Formula Weight: 129.12
• Percent Purity: ≥98%
• Chemical Name or Material: (S)-(-)-2-Pyrrolidinone-5-carboxylic acid

Safety and Handling

Hazard Category	H318
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P280-P305+P351+P338-P310
EINECSNumber	202-700-3
RTECSNumber	TW3710000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only