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  8. R 568 hydrochloride, Tocris Bioscience™

R 568 hydrochloride, Tocris Bioscience™

Catalog No. 381550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Positive allosteric modulator of human calcium-sensing receptor (CaSR)

Positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR). Exhibits calcimimetic activity. Has the ability to restore function to hCaSR mutants that cause familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT). Exerts a suppressive effect on parathyroid (PT) hormone secretion; inhibits PT cell proliferation in rats with renal insufficiency.

Chemical Identifiers

CAS 177172-49-5
Molecular Formula C18H23Cl2NO
Molecular Weight (g/mol) 340.288
InChI Key YJXUXANREVNZLH-PFEQFJNWSA-N
Synonym r 568 hydrochloride, tecalcet hydrochloride, tecalcet hcl, norcalcin, unii-3hp28r98lc, tecalcet hydrochloride usan, r-3-2-chlorophenyl-n-1-3-methoxyphenyl ethyl propan-1-amine hydrochloride, 3-2-chlorophenyl propyl 1r-1-3-methoxyphenyl ethyl amine hydrochloride
PubChem CID 158796
IUPAC Name 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine;hydrochloride
SMILES CC(C1=CC(=CC=C1)OC)NCCCC2=CC=CC=C2Cl.Cl

Specifications

Quantity 50 mg
Formula Weight 340.29
Percent Purity >99%
Chemical Name or Material R 568 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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