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QS 11, Tocris Bioscience™

Catalog No. 332450
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling

GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.

Chemical Identifiers

CAS 944328-88-5
Molecular Formula C36H33N5O2
Molecular Weight (g/mol) 567.693
InChI Key DOKZLKDGUQWMSX-HKBQPEDESA-N
Synonym qs 11 qs11,bml-wn117, 2s-2-9-4-biphenylylmethyl-2-2,3-dihydro-1h-inden-5-yloxy-9h-purin-6-yl amino-3-phenyl-1-propanol, s-2-9-1,1'-biphenyl-4-ylmethyl-2-2,3-dihydro-1h-inden-5-yl oxy-9h-purin-6-yl amino-3-phenylpropan-1-ol, 2s-2-9-1,1'-biphenyl-4-ylmethyl-2-2,3-dihydro-1h-inden-5-yloxy purin-6-yl amino-3-phenylpropan-1-ol, 2s-2-9-1,1'-biphenyl-4-yl methyl-2-2,3-dihydro-1h-inden-5-yl oxy-9h-purin-6-yl amino-3-phenylpropan-1-ol, 2s-2-2-indan-5-yloxy-9-1,1'-biphenyl-4-yl methyl-9h-purin-6-ylamino-3-phenyl-propan-1-ol, s-2-9-biphenyl-4-ylmethyl-2-2,3-dihydro-1h-inden-5-yloxy-9h-purin-6-ylamino-3-phenylpropan-1-ol
PubChem CID 42623900
IUPAC Name (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol
SMILES C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)NC(CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7

Specifications

Quantity 50 mg
Formula Weight 567.68
Percent Purity >98%
Chemical Name or Material QS 11

Safety and Handling

Recommended Storage Store at +4°C
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