Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. N-phenylureas
  8. PQ 401, Tocris Bioscience™

PQ 401, Tocris Bioscience™

Catalog No. 276850
Click to view available options
Quantity:
10mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

IGF1R inhibitor

Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.

Chemical Identifiers

CAS 196868-63-0
Molecular Formula C18H16ClN3O2
Molecular Weight (g/mol) 341.80
MDL Number MFCD00160558
InChI Key YBLWOZUPHDKFOT-UHFFFAOYSA-N
Synonym igf-1r inhibitor ii, 1-5-chloro-2-methoxyphenyl-3-2-methylquinolin-4-yl urea, unii-2n3lv83s8j, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl urea, n-2-methoxy-5-chlorophenyl-n′-2-methylquinolin-4-yl-urea, d0b4su, urea, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl, pq hplc , powder, 3-5-chloro-2-methoxyphenyl-1-2-methylquinolin-4-yl urea, n-2-methoxy-5-chlorophenyl-n'-2-methylquinolin-4-yl-urea
PubChem CID 9549305
IUPAC Name 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
SMILES COC1=C(NC(=O)NC2=C3C=CC=CC3=NC(C)=C2)C=C(Cl)C=C1

Specifications

Quantity 50 mg
Formula Weight 341.79
Percent Purity >99%
Chemical Name or Material PQ 401

Safety and Handling

Recommended Storage Store at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.