Polymixin B Sulfate, Fisher BioReagents

Description

Interferes with cytoplasmic membrane

• Polymixin B Sulfate is an antibiotic used to prevent bacterial contamination of cell cultures
• Disrupts the permeability of the cytoplasmic membrane  which leads to cell death
• This antibiotic is highly effective against gram-negative bacteria
• Intended for research use only

Specifications

Chemical Identifiers

• CAS: 1405-20-5
• Molecular Formula: C48H84N16O17S
• Molecular Weight (g/mol): 1189.36
• MDL Number: MFCD00131991
• InChI Key: HNDFYNOVSOOGDU-UHFFFAOYNA-N
• PubChem CID: 133109994
• IUPAC Name: 4-amino-N-{1-[(3-amino-1-{[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)carbamoyl]-3-hydroxypropyl}-2-formamidobutanamide; sulfuric acid
• SMILES: OS(O)(=O)=O.CC(C)CC1NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCN)NC(=O)C(CCNC(=O)C(CCO)NC(=O)C(CCN)NC(=O)C(CCN)NC1=O)NC(=O)C(CCN)NC(=O)C(CCO)NC(=O)C(CCN)NC=O

• Type: Polymixin B Sulfate
• Physical Form: Solid
• Source: Bacillus polymyxa
• Loss on Drying: < 7.0%
• Packaging: Amber Glass
• Concentration: >6000 U/mg
• Quantity: 1 g
• Merck Index: 15, 7693
• Formula Weight: 1385.61
• Percent Purity: >6000 U/mg
• Chemical Name or Material: Polymixin B Sulfate

Safety and Handling

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview Harmful if swallowed. Use personal protective equipment. Ensure adequate ventilation. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Get medical attention immediately if symptoms occur. Do not induce vomiting. Do not induce vomiting. Call a physician or Poison Control Center immediately. NFPA Health:2 Flammability:0 Instability:0

SDS