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Polymixin B Sulfate, Fisher BioReagents

Catalog No. bp29541
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Quantity:
1g
Packaging:
Amber Glass

Interferes with cytoplasmic membrane

  • Polymixin B Sulfate is an antibiotic used to prevent bacterial contamination of cell cultures
  • Disrupts the permeability of the cytoplasmic membrane  which leads to cell death
  • This antibiotic is highly effective against gram-negative bacteria
  • Intended for research use only

Chemical Identifiers

CAS 1405-20-5
Molecular Formula C56H100N16O17S
Molecular Weight (g/mol) 1301.571
InChI Key HFMDLUQUEXNBOP-ZFUOWTTOSA-N
PubChem CID 133109994
IUPAC Name N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,18R)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-ox
SMILES CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O

Specifications

Identification Pass Test
Loss on Drying < 7.0%
Merck Index 15, 7693
Packaging Amber Glass
Formula Weight 1385.61
Physical Form Solid
Percent Purity > 6000 U/mg
Concentration >6000 U/mg
Quantity 1g
Source Bacillus polymyxa
Chemical Name or Material Polymixin B Sulfate
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Hazard Statement WARNING!
Precautionary Statement Emergency Overview
Harmful if swallowed. Use personal protective equipment. Ensure adequate ventilation. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Get medical attention immediately if symptoms occur. Do not induce vomiting. Do not induce vomiting. Call a physician or Poison Control Center immediately.

NFPA

Health:2
Flammability:0
Instability:0
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