Thermo Scientific™ SIA (succinimidyl iodoacetate)

Crosslink amines to sulfhydryls with this very short crosslinker composed of NHS-ester and iodoacetyl (haloacetyl) groups at ends of a 3-atom (1.5A) spacer arm.

Supplier:  Thermo Scientific™ 22349

Catalog No. PI22349

Description

Thermo Scientific™ Pierce SIA is a very short (1.5 Å) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Suited to capturing amine and sulfhydryl groups in very close proximity

Highlights:

• Reactive groups: NHS ester and iodoacetyl
• Reactive toward: amino and sulfhydryl groups

Specifications

• Chemical Reactivity: Amine-Sulfhydryl
• Description: SIA
• PEGylated: No
• Content And Storage: Upon receipt store at 4°C protected from moisture.
• Shipping Condition: Ambient
• Labeling Method: Chemical Labeling
• Reactive Moiety: Haloacetyl, NHS Ester
• Form: Solid
• Solubility: DMF, DMSO
• Water Soluble: No

• Cleavable: No
• Molecular Weight (g/mol): 283.02
• Spacer Arm Length: 1.5 Å
• Cell Permeability: Yes
• Product Line: Pierce™
• Crosslinker Type: Heterobifunctional
• Spacer: Short (<10 Å)
• Quantity: 50 mg
• Format: Standard
• Product Type: Crosslinker

For Research Use Only. Not for use in diagnostic procedures.