Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Furopyridines
  7. PI 103 hydrochloride, Tocris Bioscience™

PI 103 hydrochloride, Tocris Bioscience™

Catalog No. 293010
Click to view available options
Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.

Chemical Identifiers

CAS 371935-79-4
Molecular Formula C19H17ClN4O3
Molecular Weight (g/mol) 384.82
InChI Key XSQMYBFFYPTMFE-UHFFFAOYSA-N
Synonym pi 103 hydrochloride, pi-103 hydrochloride, pi103 hydrochloride, pubchem22442, pi-103, hydrochloride, c19h16n4o3.clh, pi 103 hydrochloride;pi103 hydrochloride, 3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride, 3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
PubChem CID 16739368
IUPAC Name 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl

Specifications

Quantity 10 mg
Formula Weight 384.82
Percent Purity >98%
Chemical Name or Material PI 103 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.