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PEP 005, Tocris Bioscience™

Catalog No. 40541
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Protein kinase C activator

Activator of protein kinase C (PKC). Exhibits antileukemic activity; induces nuclear translocation of PKCδ, and induces apoptosis in acute myeloid leukemia (AML) cell lines and primary AML blast cells. Also displays antiproliferative effects and induces apoptosis in Colo205 cells. Reactivates latent HIV in cell culture. Also acts as a substrate for multidrug transporter.

Chemical Identifiers

CAS 75567-37-2
Molecular Formula C25H34O6
Molecular Weight (g/mol) 430.54
MDL Number MFCD07784504
InChI Key VDJHFHXMUKFKET-WDUFCVPESA-N
Synonym 4s,5s,6r,14r-5,6-dihydroxy-7-hydroxymethyl-3,11,11,14-tetramethyl-15-oxotetracyclo 7.5.1.0 1 ,?.0 1 ?, 1 2 pentadeca-2,7-dien-4-yl 2z-2-methylbut-2-enoate
PubChem CID 92043127
IUPAC Name (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2Z)-2-methylbut-2-enoate
SMILES C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C

Specifications

Quantity 1 mg
Formula Weight 430.53
Percent Purity >98%
Chemical Name or Material PEP 005
Recommended Storage Store at -20°C
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