β-Nicotinamide Adenine Dinucleotide, MP Biomedicals™

Description

Acts as a major electron acceptor molecule in biological oxidations. β-Nicotinamide Adenine Dinucleotide, MP Biomedicals serves as a coenzyme of the dehydrogenases and acts as a hydrogen acceptor. β-NAD is one of the biologically active forms of

β-NAD occurs in living cells primarily in the oxidized state.

• Serves as a coenzyme of hydride-transfer enzymes in dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols
• Usually acts as a hydrogen acceptor, forming NADH, which then serves as a hydrogen donor in the respiratory chain
• Used as a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins
• Recently reported to be a P2Y11 agonist

Specifications

Chemical Identifiers

• CAS: 53-84-9
• Molecular Formula: C21H26N7O14P2-
• Molecular Weight (g/mol): 662.422
• InChI Key: BAWFJGJZGIEFAR-NNYOXOHSSA-M
• Synonym: nicotinamide adenine dinucleotide, nad+, diphosphopyridine nucleotide, nad-oxidized, nicotinamide-adenine dinucleotide, dpn-ox, beta-nicotinamide adenine dinucleotide, dpn+, nad, nad +
• PubChem CID: 15938971
• ChEBI: CHEBI:57540
• IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C4N=CN=C5N)O)O)O)O)C(=O)N

• Absorbance: λ max (water): 259 ± 3nm
• Melting Point: 160°C (literature)
• pH: 2 to 4 (1% aq. soln.)
• Quantity: 500 mg
• Solubility Information: Soluble in water (200mg/mL)
• Formula Weight: 663.4 (anhydrous)
• Percent Purity: ≥98%
• Physical Form: Powder

Safety and Handling

Recommended Storage

0°C, desiccate