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NBQX, Tocris Bioscience™

Catalog No. 037350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent AMPA antagonist; more selective than CNQX (Cat. No. 0190)

NBQX is a selective and competitive AMPA and kainate receptor antagonist (IC50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo.

NBQX disodium salt, a more water-soluble form of NBQX, also available.

Chemical Identifiers

CAS 118876-58-7
Molecular Formula C12H8N4O6S
Molecular Weight (g/mol) 336.278
InChI Key UQNAFPHGVPVTAL-UHFFFAOYSA-N
Synonym nbqx, 2,3-dioxo-6-nitro-7-sulfamoylbenzo f quinoxaline, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo f quinoxaline, 6-nitro-7-sulfamoylbenzo f quinoxaline-2,3-dione, 6-nitro-2,3-dioxo-1,4-dihydrobenzo f quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxobenzo f quinoxaline-8-sulfonamide, 6-nitro-7-sulphamoylbenzo f quinoxaline-2,3-dione, 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo f quinoxaline, 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo f-quinoxaline
PubChem CID 3272524
ChEBI CHEBI:31073
IUPAC Name 6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
SMILES C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3

Specifications

Quantity 50 mg
Formula Weight 336.28
Percent Purity >98%
Chemical Name or Material NBQX

Safety and Handling

Recommended Storage Store at Room Temperature
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